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Results for: Center for Drug Discovery
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Chemistry’s Emily Mevers utilizes marine egg masses for medical innovations , articleMevers, of the Department of Chemistry, received a five-year, $1.9 million grant from the National Institutes of Health that aims to leverage the microbiomes of marine egg masses for the development of next-generation antibiotics to treat emerging pathogens.
Date: Oct 10, 2022 -
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Webster Santos brings molecule inhibitor discovery in chronic kidney disease closer to drug treatment , articleChronic kidney disease almost certainly ends in fatal renal failure. The costs are enormous, not only in lives, but also to the economy. According to 2017 estimates, chronic kidney disease cost the U.S. economy $84 billion, and end-stage renal disease treatment added another $36 billion.
Date: Aug 23, 2022 -
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Inventor spotlight: Paul Carlier, professor of chemistry and director of the Virginia Tech Center for Drug Discovery , articleFueled by a passion for science, Carlier is a medicinal chemist who harnesses the power of synthetic chemistry to advance biology, medicine, and public health.
Date: May 27, 2022 -
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Virginia Tech Center for Drug Discovery supports drug and therapeutic development , articleThe center supports areas ranging from cancer to neuroscience to obesity to infectious disease to agricultural insecticides.
Date: Apr 11, 2022 -
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Breaking the deadly cycle: Drug researchers tackle the malaria parasite at multiple life stages , articleResearchers have received a $3.7 million grant from the National Institutes of Health to begin further testing of two inexpensive and effective antimalarial drug candidates that can kill Plasmodium parasites at three stages of their development.
Date: Aug 30, 2021 -
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Virginia Tech drug researcher receives $2.2 million NIH grant to further develop ‘fat burning’ molecule , articleWebster Santos, a professor of chemistry in the College of Science, has received a $2.2 million grant from the National Institutes of Health to further his recent research with mitochondrial uncouplers - small "fat burning" molecules that could be used to help treat NASH.
Date: Jun 11, 2021 -
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Researcher receives NSF grant to study the structure and function of enzymes, antibiotic implications , articleAfter recently receiving a grant from the Chemistry Division of the National Science Foundation, Pablo Sobrado and researchers from the University of Missouri are gearing up to uncover the inner workings of flavoenzymes, an up-and-coming enzyme family that shows some promise for the improvement of human health.
Date: Oct 01, 2020 -
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Board of Visitors honors chemistry’s David G.I. Kingston with emeritus status , articleKingston, University Distinguished Professor of Chemistry in the College of Science and a member of the Virginia Tech community since 1971, made significant contributions to biodiversity conservation, drug development, and natural products research.
Date: Jul 06, 2020 -
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Virginia Tech drug researcher develops ‘fat burning’ molecule that has implications for treatment of obesity , articleSantos and his colleagues have recently identified a small mitochondrial uncoupler, named BAM15, that holds promise for future treatment and prevention of obesity, diabetes, and especially nonalcoholic steatohepatitis, a type of fatty liver disease.
Date: Jun 05, 2020 -
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Virginia Tech announces expansive cancer research initiative , articleVirginia Tech has developed a university-wide cancer research strategy to create and expand synergies among more than 30 existing research teams at work finding new ways to diagnose and treat cancer.
Date: Oct 16, 2019 -
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Virginia Drug Discovery Consortium meeting to focus on opioids, addiction, data science , articleThe Virginia Tech Center for Drug Discovery will host a May 21-22 meeting of the Virginia Drug Discovery Consortium to be held at the Hotel Roanoke, with such topics as opioid abuse, addiction, and data science in medicine as topics.
Date: May 17, 2019 -
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Drug hunters awarded $2.8 million to develop a drug to treat multiple sclerosis , articleWebster Santos, professor of chemistry and the Cliff and Agnes Lilly Faculty Fellow in the College of Science at Virginia Tech, recently received a $2.8 million award from the National Institute of Allergy and Infectious Diseases to discover drugs to inhibit a small molecule transporter.
Date: Mar 08, 2019 -
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Virginia Tech research into genetics of mosquito reproduction could help stop spread of disease , articleThe long-term goal is to use genetic engineering and chemical intervention to suppress mosquito populations and impede their ability to transmit diseases.
Date: Aug 31, 2018 -
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Drug researcher receives $1.2 million to find compounds to treat fatty liver disease , articleA grant, along with the matching funds, will support Webster Santos' research to develop drugs to treat nonalcoholic steatohepatitis, a type of non-alcoholic fatty liver disease.
Date: Aug 14, 2018 -
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Virginia Tech researchers discover insights into HIV with implications for drug development , article“We hope this new insight on the druggable surface of HIV will provide routes to novel types of therapeutics to combat this virus that has taken so many lives,” said Anne M. Brown, an assistant professor in research and informatics in University Libraries and an adjunct professor in the Department of Biochemistry in the College of Agriculture and Life Sciences.
Date: Jul 09, 2018 -
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Researchers discover insights into amyloids associated with Alzheimer’s and type 2 diabetes , articleA Virginia Tech research team's findings were recently published in the Journal of Molecular Biology.
Date: Jun 25, 2018 -
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Drug discovery researcher receives NIH support to find inhibitors to treat global diseases , articlePablo Sobrado has received a $558,747 grant from the NIH to screen small chemical libraries to find inhibitors for an enzyme that supports fungal and parasitic infections.
Date: May 31, 2018 -
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Researchers discover new mechanism of antibiotic resistance in leprosy and tuberculosis , articleKnowledge of this mechanism will ultimately allow researchers to design more effective drugs to treat these diseases.
Date: Apr 16, 2018 -
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Chemistry's Webster Santos reappointed Cliff and Agnes Lilly Faculty Fellow , articleSantos is a member of the Virginia Tech Center for Drug Discovery and the Virginia Drug Discovery Consortium, and is an expert medicinal chemist whose research focuses on compounds with new modes of action to treat kidney fibrosis, fatty liver disease, neurodegenerative diseases, traumatic brain injury, stroke, and aging.
Date: Nov 14, 2017 -
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Researchers discover compounds that could decrease fungal infection in lungs , articleTwo naturally occurring compounds — identified in the small molecule library available at the Virginia Tech Center for Drug Discovery Screening Laboratory supported by the Fralin Life Science Institute — work against an enzyme important in cell wall production in the deadly fungus, called Aspergillus fumigatus.
Date: Sep 13, 2017
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